Archive for the 'Microarrays' Category

Installing Birdsuite – Not Fun.

Birdsuite is an application released by the Broad (Harvard/MIT) for analysing Affy SNP 6.0 array data. It was published in Nature Genetics. The installation process is really shockingly bad. Its a little surprising that journal like Nature Genetics can possibly justify publishing a piece of software in this condition. You would have to question whether [...]

Steps in Preprocessing Affymetrix GeneChip Data

The analysis of microarray data to produce lists of differentially expressed genes has several steps which can differ based on the type of data being assayed. However, all data follows the same general pipeline which involves reading raw data, quality assessing the data, removing bad spots/arrays from further analysis, preprocessing the data and calculating differential [...]

What Are DNA Microarrays

As a prerequisite to this article you must understand what genes, DNA, proteins and mRNA are. You can find our short introduction to these concepts here.
DNA microarrays are a high throughput technology used to measure the expression levels of thousands of genes, in some cases all of the genes in a genome, simultaneously. The fundamental [...]