The analysis of microarray data to produce lists of differentially expressed genes has several steps which can differ based on the type of data being assayed. However, all data follows the same general pipeline which involves reading raw data, quality assessing the data, removing bad spots/arrays from further analysis, preprocessing the data and calculating differential [...]
As a prerequisite to this article you must understand what genes, DNA, proteins and mRNA are. You can find our short introduction to these concepts here.
DNA microarrays are a high throughput technology used to measure the expression levels of thousands of genes, in some cases all of the genes in a genome, simultaneously. The fundamental [...]
Eukaryotes are organisms whose cells are organized into complex structures enclosed within membranes. Most eukaryotic organisms, for example, human beings, contains billions of individual cells. Almost all of these cells contain, within each nucleus, the entire genome for that organism. This genome contains the organism’s complete hereditary information in the form of deoxyribonucleic acid (DNA), [...]